ABOUT THE ROLE
- Date Posted - 22/02/2023
- London
- Associate Director – Assay Development Leader, Drug Discovery
- Starting From 61,500 per annum
- Interest in this position?
Get in touch with us! - hello@northreach.uk
or submit your CV belowAssociate Director – Assay Development Leader, Drug Discovery
The company is a privately-owned biopharmaceutical company on the look out for an experienced Associate Director that will act as the Assay Developemt Leader in a pivotal time in the company’s journey as they drive their small molecule programmes towards the clinic!
MAIN RESPONSIBILITIES
- Contribute to project progression by designing and implementing biochemical and cell-based screening and profiling assays and designing screening cascades to identify molecules with characteristics meeting the Therapeutic Target Profile.
- Lead a team of assay development and screening scientists.
- Develop, evaluate, optimise and implement novel technologies and methods for process improvement.
- Analyse, interpret and report research findings.
- Play a key role in the strategy and the decision-making process to select best drug molecule candidates.
- Collate results, manage drug molecule data within the project and contribute to reports where applicable.
EXPERIENCE WE ARE LOOKING FOR (E – Essential P – Preferred)
- Experience with 2D & 3D cell-based assays e.g., binding and blocking assays, reporter assays, signalling assays, mediator release
- Experience with biochemical assays such as ELISA, Luminex, HTRF, Alphascreen and FRET
- Determination of drug EC50 and IC50 and monitoring of key QC parameters
- Prior experience with using automation for drug screening
- Experience of multi-colour flow cytometry and isolation and identification of immune cells would be a further advantage.
- Several years of line management experience, work well within a team, to have strong written and verbal communication skills, as well as good IT skills.
- Confidence in troubleshooting, methodical, well organised, pay close attention to detail, and maintain accurate records.
- PhD or MSc with experience in Biomedical sciences, Biochemistry, Biotechnology or related disciplines
- 8+ years’ experience working in laboratory research in a contract research/biotech/pharma industry environment triaging small molecules in drug discovery.
Apply Now
To apply for this job email your details to hello@northreach.uk
